Mesothelioma Clinical Trials Search Tool
Find and explore mesothelioma clinical trials with our easy-to-use search tool and get connected with doctors conducting them. Search by location, trial phase, and specific disease presentation to discover cutting-edge treatment opportunities that may fit your diagnosis.
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Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma
Address: 221 Longwood Ave room 108, Boston, MA 02115, USA
Phone: 877-451-7009
Mesothelioma Type:
- Pleural: No
- Peritoneal: Yes
- Pericardial: No
- Tunica Vaginalis: No
- Therapy Targeted: No
Type: Epitheliod, Biphasic, Sarcomatoid
Condition: Peritoneal Malignant Mesothelioma
Description: This phase II trial compares the usual treatment alone to using immunotherapy (atezolizumab) plus the usual treatment in treating patients with peritoneal mesothelioma. The usual treatment consists of surgery or chemotherapy. Chemotherapy drugs, such as carboplatin and pemetrexed, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving atezolizumab with usual treatment may work better than usual treatment alone.
Research Center: Alliance for Clinical Trials in Oncology
Treatment Interventions: BIOLOGICAL: Atezolizumab, BIOLOGICAL: Bevacizumab, PROCEDURE: Biospecimen Collection, DRUG: Carboplatin, PROCEDURE: Computed Tomography, PROCEDURE: Cytoreductive Surgery, DRUG: Pemetrexed, PROCEDURE: Positron Emission Tomography
Clinical Trial Number: NCT05001880
Phase: Phase 2
Status: Recruiting
