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Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma
Address: 1515 Holcombe Blvd, Houston, TX 77030, USA
Phone: 877-451-7009
Mesothelioma Type:
- Pleural: False
- Peritoneal: False
- Pericardial: False
- Tunica Vaginalis: False
Type: N/A
Condition: Advanced Renal Cell Carcinoma, Advanced Mesothelioma, Advanced Osteosarcoma
Description: To find a recommended dose of donated NK cells that can be given with lymphodepleting chemotherapy to patients with advanced renal cell carcinoma, mesothelioma, or osteosarcoma. The effects of this therapy will also be studied.
Research Center: MD Anderson Cancer Center
Treatment Interventions: DRUG: CAR.70/IL15-transduced CB-derived NK cells, DRUG: Fludarabine phosphate, DRUG: Cyclophosphamide
Potential Impact: Fake Data
Clinical Trial Number: NCT05703854
Phase: Phase 1, Phase 2
Status: Recruiting