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Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Address: 1515 Holcombe Blvd, Houston, TX 77030, USA

Phone: 877-451-7009

Mesothelioma Type:

  • Pleural: False
  • Peritoneal: False
  • Pericardial: False
  • Tunica Vaginalis: False

Type: N/A

Condition: Advanced Renal Cell Carcinoma, Advanced Mesothelioma, Advanced Osteosarcoma

Description: To find a recommended dose of donated NK cells that can be given with lymphodepleting chemotherapy to patients with advanced renal cell carcinoma, mesothelioma, or osteosarcoma. The effects of this therapy will also be studied.

Research Center: MD Anderson Cancer Center

Treatment Interventions: DRUG: CAR.70/IL15-transduced CB-derived NK cells, DRUG: Fludarabine phosphate, DRUG: Cyclophosphamide

Potential Impact: Fake Data

Clinical Trial Number: NCT05703854

Phase: Phase 1, Phase 2

Status: Recruiting

Website: https://clinicaltrials.gov/study/NCT05703854

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