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SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Address: 1515 Holcombe Blvd, Houston, TX 77030, USA

Phone: 877-451-7009

Mesothelioma Type:

  • Pleural: True
  • Peritoneal: True
  • Pericardial: True
  • Tunica Vaginalis: True

Type: Epitheliod

Condition: Ovarian Cancer, Cholangiocarcinoma Recurrent, Malignant Mesothelioma

Description: This first-in-human (FIH) trial is designed to assess the safety, feasibility, and potential activity of a single intravenous (IV) dose of SynKIR-110 administered to subjects with mesothelin-expressing advanced ovarian cancer, mesothelioma, and cholangiocarcinoma.

Research Center: MD Anderson Cancer Center

Treatment Interventions: BIOLOGICAL: SynKIR-110, Autologous T cells Transduced with Mesothelin KIR-CAR

Potential Impact: High

Clinical Trial Number: NCT05568680

Phase: Phase 1

Status: Recruiting

Website: https://clinicaltrials.gov/study/NCT05568680

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