Mesothelioma Articles: Page 1 of 11

First New Drug Treatment for Mesothelioma Approved by FDA in Over 16 Years

• October 9, 2020
• Lisa Hyde-Barrett
• Mesothelioma, Research, Treatments

For the first time in 16 years, the U.S. Food & Drug Administration has approved a new drug combination specifically for the treatment of malignant pleural mesothelioma. The two drugs, which are to be used together when surgery is not an option, are Opdivo (nivolumab) and Yervoy (ipilimumab). About 20,000 Americans are diagnosed with malignant pleural mesothelioma each year according to the FDA – the vast majority of which have tumors at diagnosis that cannot be removed by surgery. The [...]

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New Dual-Immunotherapy Regimen Proves Effective for Mesothelioma Patients in Phase 3 Clinical Trial

• August 17, 2020
• Joseph Belluck
• Mesothelioma, Research, Treatments

Dr. Paul Baas of the Netherlands Cancer Institute and the University of Leiden in Amsterdam recently presented on the CheckMate 743 study at the International Association for the Study of Lung Cancer World Conference. The randomized phase III Checkmate 743 clinical trial prescribed mesothelioma patients who were not candidates for surgery with a combination of first-line nivolumab and ipilimumab. The promising results yielded a four-month improvement in median overall survival for patients [...]

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Clinical Trial of Imfinzi (Durvalumab) in Conjunction with Chemotherapy Yields Significantly Longer Survival Time for Patients Diagnosed with Malignant Pleural Mesothelioma

• July 28, 2020
• Joseph Belluck
• Mesothelioma, Research, Treatments

Immuno-Oncology News recently published results of a Phase 2 clinical trial of the immuno-checkpoint inhibitor Imfinzi (durvalumab) for patients diagnosed with malignant pleural mesothelioma.  The PrECOG cancer research group tested the effects of pairing Imfinzi, an AstraZeneca drug that blocks the activity of the PD-1 receptor in immune T-cells, with standard chemotherapy on a group of 55 individuals who had been recently diagnosed with inoperable malignant pleural mesothelioma. The [...]

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Pairing Machine Learning with PET Scans Can Help Predict Mesothelioma Outcomes

• July 24, 2020
• David Belsky
• Mesothelioma, Research, Treatments

The EJNMMI Research medical journal recently published an article entitled “FDG PET versus CT radiomics to predict outcome in malignant pleural mesothelioma patients” that outlines a study wherein 72 patients diagnosed with malignant pleural mesothelioma (MPM) at the University Hospital Zurich underwent pre-treatment FDG PET and CT scans alongside curative treatments. In the study, Swiss researchers discovered that using machine-learning radiomics models in conjunction with PET scans to [...]

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Mesothelioma Patients Can Safely Get Treatment Through Telehealth and Video

• July 14, 2020
• Lisa Hyde-Barrett
• Mesothelioma, Nurse's Corner, Patients, Treatments

The COVID-19 virus has disrupted all of our lives and routines. Things that we always did and places we always went are no longer available. The pandemic has forced us to all look at things we routinely do and challenged us to do them differently. Like in business, in medicine sometimes small disruptions can lead to larger innovative changes. In the treatment of malignant mesothelioma, disruptors have led the way. Over the years we have seen doctors challenging the previously held belief [...]

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