Mesothelioma Help Cancer News
Holding My Father’s Music Close to My Heart
My father never claimed to be a musician. He said he just “played at” the guitar but loved singing and playing with his band. Dad began singing at Church when I was little, and he practiced constantly, his latest choice of song would be stuck in my head for days. Many Saturday mornings were spent with him at the Christian book store, listening to new music, carefully choosing one. He had specific criteria that he looked for when he decided on which song to pick. He loved songs that were a bit country, classic, and told a story.
I remember many times, listening to him sing, so full of pride that my eyes would fill with tears. It happened often, but always on Easter when he sang a song called “The Hammer.” It never failed that I would have to look away from him so that I wouldn’t sob. The powerful message of the music, coupled with the humility of the man singing it, were almost too much for me. Now, every time I think of that song, I instantly feel sad.
When I was little, Dad always sang “You Are My Sunshine” to me. It kind of became our song. On my wedding day, before he walked me down the aisle, he handed me a gold box containing a necklace with the lyric engraved on it. It is something that I will treasure forever.
Music means a lot to me, in that I find a lot of comfort in its message; it seems like, I too, enjoy a song with a story… another trait that I inherited from my father. It makes me smile, hearing ones that I would sing with Dad, or that he thought were funny or made no sense! It seemed like Dad always had a song in his heart, and that song exuded from him like a beautiful beam of sunshine.
I love having musical memories of someone who I loved, and still love, so very much. These are some of my favorite memories that I will always hold close to my heart.
Combination of Electric Fields and Chemotherapy May Be A New Treatment Option for Pleural Mesothelioma Patients
The key to increasing survival for mesothelioma patients is to kill the cancer cells before they can spread to other organs. Treatment options, including surgery, chemotherapy and radiation, all contribute to a patient’s survival, but many times the prognosis remains unchanged. Now, one company has turned to experimenting with delivering electromagnetic waves to the chest of pleural mesothelioma patients and reports improvements in overall survival when combined with chemotherapy.
Novocure, a UK-based medical device company that develops and markets Tumor Treating Fields delivery systems, developed the novel devices as an alternative way to destroy tumor cells while sparing healthy tissue. Already approved by the U.S. Food and Drug Administration for the treatment of brain cancer, the device is now in a Phase II clinical trial for pleural mesothelioma patients.
In April, researchers gave an interim review of the STELLAR clinical trial reporting that the first 42 pleural mesothelioma patients treated with the combination of Tumor Treating Fields (TTF) and pemetrexed and cisplatin or carboplatin had a one-year survival rate of 80 percent, compared to 50 percent in the chemotherapy only patients. Median progression free survival was 7.3 months versus just 5.7 months in the chemotherapy controlled group.
“We are extremely pleased with these top-line results, which bring us one step closer to realizing the potential for a new treatment for mesothelioma patients in desperate need,” said Dr. Eilon Kirson, Novocure’s Chief Science Officer and Head of Research and Development, in an April 17 press release.
The NovoTTF-100L device used in the clinical trial provides mesothelioma patients with a round-the-clock treatment option that allows them to maintain an active lifestyle without interference to activities such as walking outdoors, shopping, and cleaning. Connected to the patient via insulated electrode arrays placed on the upper torso, the device delivers low-intensity alternating electric fields to the region near the mesothelioma tumors. The TTF is inconspicuous and light enough to carry to most functions and activities. The device needs to be active approximately 18 hours a day. According to the company’s website there are no limiting side effects.
“Mesothelioma is the first torso indication for which Novocure will pursue FDA approval,” said Dr. Kirson.
Novocure previously received a Humanitarian Use Device (HUD) designation for the use of TTF for pleural mesothelioma. The next step is to submit a Humanitarian Device Exemption (HDE) application to the FDA. For medical devices, an HDE exempts the businesses from proving effectiveness of the device. However, the company must show that the HUD “will not expose patients to an unreasonable or significant risk of illness or injury and the probable benefit to health from use of the device outweighs the risk of injury or illness from its use, ” according to the HDE application requirements.
Pleural mesothelioma, a rare form of cancer affecting the lining of the lungs, is highly aggressive and is resistant to many cancer treatments. Most often diagnoses are not made until symptoms appear and the disease has progressed to an advanced stage leaving the patient with life-threatening complications. 3,000 Americans are diagnosed with mesothelioma each year.
Sources :
- STELLAR clinical trial
https://clinicaltrials.gov/ct2/show/NCT02397928 - Novocure’s Chief Science Officer and Head of Research and Development
https://www.novocure.com/novocure-reports-positive-top-line-results-from-stellar-phase-2-pilot-trial-in-mesothelioma/ - NovoTTF-100L
https://www.novocuretrial.com/stellar-mesothelioma/living-with-ttfields/ - Humanitarian Device Exemption
https://www.fda.gov/medicaldevices/deviceregulationandguidance/howtomarketyourdevice/premarketsubmissions/humanitariandeviceexemption/default.htm - HDE application requirements
https://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/HowtoMarketYourDevice/PremarketSubmissions/HumanitarianDeviceExemption/ucm563286.htm
Do You Hear What I Hear? Mesothelioma Nurse Explains What Can Influence What You Hear
When you visit the doctor when you are dealing with a frightening diagnosis such as malignant mesothelioma, it is easy to get a little confused while you try to familiarize yourself with new medical terms. You may hear something one way, but your support person, who was also at the appointment, heard something different. This can happen to anyone. There are reasons for hearing the same words, but not hearing what the person is trying to say.
There is a four-second audio clip going around the internet that is an example of how people hear differently. People are divided into two camps on what they hear in the computer-generated clip: half hear “Laurel” while the other half hear “Yanny.” When you say those words they sound totally different. How can people hear the same clip, but interpret it differently?
There are actually scientific reasons that can explain why we hear one or the other. Whether someone hears Laurel or Yanny can depend on how old they are- as we age our ears hear fewer sounds on the high pitched range. Those folks will hear Laurel. What you are hearing the audio clip on also can influence what you hear. The more high pitched the sound or tinny the speakers , the more people hear Yanny. There is also the element of someone putting the suggestion into your brain by asking in advance what do you hear, Yanny or Laurel. This can influence what you hear.
When you are at important medical appointments, remember to ask for clarification from your team. Repeat what you understand you heard. Clarification, explaining your understanding of the information, and repeating it out loud, can all help to avoid misinformation.
Communication and interpretation must be clear so that the same message is heard by both the patient and the family member.
Yanny or Laurel is an interesting, fun clip on the internet. It shows how easily we can hear things differently. But it is also a lesson in discussing what it is you are hearing when it comes to your mesothelioma treatment.
Honor our Fallen Veterans This Memorial Day
Pools open across the U.S., families flock to the beach, and school-aged kids look forward to summer vacation on Memorial Day. Although the day is seen as the unofficial start of summer, it is meant to honor all those who died while serving in the U.S. military.
According to USMemorialDay.org, over 1.8 million soldiers have given their lives for America since 1775. Among foreign wars, World War II was the deadliest for the U.S. with 405,399 lives lost. The number of U.S. military personnel killed in the Korean War was 33,686, and in the Vietnam War 58,209. Current U.S. wars in Iraq and Afghanistan have claimed over 7,000 American lives.
Still more lost their lives long after the battlefield or service from injuries or illnesses, such as mesothelioma, suffered from their service. Some U.S. soldiers have successfully ended their military career only to be stricken with health issues later due to exposure to toxic materials, including asbestos.
According to the U.S. Department of Veterans Affairs, veterans who served in any of the following occupations may have been exposed to asbestos: mining, milling, shipyard work, insulation work, demolition of old buildings, carpentry and construction, manufacturing and installation of products such as flooring and roofing. In addition, the VA reports that the latest generation of war veterans, those who served in Iraq and other countries in that region, could have been exposed to asbestos when older buildings were damaged and the contaminants were released into the air.
The inhalation of asbestos fibers has been associated with lung cancer and mesothelioma. Pleural mesothelioma is a rare cancer affecting the lining of the lungs that is extremely difficult to treat and is virtually impossible to cure. Although nearly 3,000 new cases are reported annually in the U.S., statistics show that military veterans account for over one-third of those cases.
All of us at MesotheliomaHelp encourage all Americans to take a moment out of your busy Memorial Day to honor those who have served our country. In coordination with the National Moment of Remembrance, observed at 3:00pm local time, “pause for one minute … to remember and reflect on the sacrifices made by so many to provide freedom for all.”
Sources
- U.S. Department of Veterans Affairs
http://www.publichealth.va.gov/exposures/asbestos/index.asp - National Moment of Remembrance
http://www.usmemorialday.org/?p=97
Nurses Make A Difference to Mesothelioma Patients
Nurses are an integral part to anyone’s recovery. During my father’s battle with mesothelioma, there were countless nurses on his medical team, cheering him on, taking care of him, and becoming his friends. They were each very special to me and my family, and we still appreciate all that they did to make my Dad feel like he mattered, and that he was being cared for by caring people.
When Dad had his pleurectomy at NYU Langone, there was a nurse’s aide named Doris. Dad enjoyed his time with her so much; I remember leaving the hospital when he was released back to the hotel and she wasn’t working at the time. We left a note on the white board in the room, thanking her and reiterating their inside joke once more, hoping that it would still be there when her next shift began.
Dad spent a fair amount of time in treatment facilities and hospitals, and he would always talk about the nurses as though they were his buddies. I know that they have an incredibly hard job that must wear them down at times. I just pray that my father was a bright light in their day, as they were in his.
On behalf of mesothelioma patients and their families, thank you for all you do. Your hard work and dedication do not go unnoticed.
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